Abstract

The present work is dedicated to study of the possibilities of improving the production method of 11C and 18F medical isotopes using a linear electron accelerator. Experimental studies of 11C and 18F isotopes production by the photonuclear technique were carried out in [1]. Various targets were irradiated by bremsstrahlung photons following by measurements targets’ activities. This experimental research has been carried out in the energy range from 10 to 40 MeV. The current work studies an angular distribution of bremsstrahlung photons in order to estimate the possibilities of producing maximum achievable levels of medical isotopes 18F and 11С activities. The angular distribution of bremsstrahlung photons is an important property of the irradiation stand which contains an assembly of targets. This important property allows designing necessary changes in the target assembly setup used to produce medical isotopes. The research presented in the current work was done as a computer simulation. The computer software package ‘KIPT’ was developed in С++ programming language, using the Geant4 toolkit in order to obtain the angular distribution of bremsstrahlung photons. Experimental setup materials as well as structural elements positions were defined in the DetectorConstruction class of our program. The parameters of an electron beam were defined in the PrimaryGeneratorAction class. The electron beam diameter was defined as 8 mm, energy Ее=36.7 MeV, corresponding to the real experiment carried out at the “Accelerator” Science and Research Establishment of Kharkiv Institute of Physics and Technology [1]. Models of physical processes occurring while the electron beam crosses the target assembly were defined in the PhysicsList class. All classes and modules necessary for the analysis of simulation results were included to our program together with visualization modules. Visualization modules use the OpenGL graphics library and the Qt5 software to represent the relative position of experimental setup parts and to visualize particle trajectories. As a result of this work, the angular distributions were obtained for the beam of electrons and bremsstrahlung photons directly before the target. This result will allow target assembly parameter optimization for optimal production of medical isotopes by the photonuclear technique.

Highlights

  • The use of radionuclides in nuclear medicine, biology as well as to assess the state of the environment and in other areas is widespread

  • This work is an assessment of the method of computer simulation of electrons and bremsstrahlung photons angular distributions for the experimental setup described in [1]

  • Fluorine interacts with incident gamma rays, and final products are formed as a result of a nuclear reaction – the fluorine isotope

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Summary

EAST EUROPEAN JOURNAL OF PHYSICS

The present work is dedicated to study of the possibilities of improving the production method of 11C and 18F medical isotopes using a linear electron accelerator. The current work studies an angular distribution of bremsstrahlung photons in order to estimate the possibilities of producing maximum achievable levels of medical isotopes 18F and 11С activities. As a result of this work, the angular distributions were obtained for the beam of electrons and bremsstrahlung photons directly before the target This result will allow target assembly parameter optimization for optimal production of medical isotopes by the photonuclear technique. The target irradiation by bremsstrahlung flux is carried out to study the possibility of obtaining the maximum achievable activity levels of medical isotopes (in particular, 11C and 18F ) using a linear electron accelerator. This work is an assessment of the method of computer simulation of electrons and bremsstrahlung photons angular distributions for the experimental setup described in [1]

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