Abstract
Complex treatment after pathohistological and immunohistochemical analysis in synchronous neoplasms - anorectal achromatic malignant melanoma and gastric extrapleural solitary fibrous tumor
Highlights
Anorectal malignant melanoma (ARMM) is an extremely rare and very aggressive disease with a very poor prognosis [1,2,3,4,5]
After complex treatment, including surgery and adjuvant radiotherapy of the RMM and surgery of the gastric tumor, we report a one-year disease-free survival with a good quality of life
Melanocytes may appear in the three regions, the occurrence of melanoma is more frequent in the transition zone and squamous epithelium [17,18,19,20,21,22,23,24]
Summary
Anorectal malignant melanoma (ARMM) is an extremely rare and very aggressive disease with a very poor prognosis [1,2,3,4,5]. Marinova L (2020) Complex treatment after pathohistological and immunohistochemical analysis in synchronous neoplasms - anorectal achromatic malignant melanoma and gastric extrapleural solitary fibrous tumor the upper surface, a solid component in the lateral part, as well as a hypokinetic area near the mucosa. Soft tissue tumor of the stomach, located submucosally with the involvement of the tunica muscularis. It consists of randomly arranged cells of different types: those with round nuclei, others with small elongated nuclei and others with morphology of single and multilocular lipoblasts with low mitotic activity (Figures 2A , 2B and 3). 1) After IHC: Achromatic malignant melanoma of the rectum - small cell variant pT3pN0Mx G3/ Stage II; 2) After IHC: Benign variant of gastric solitary fibrous tumor. After one year from the diagnosis of synchronous tumors, the patient is without local recurrence and distant metastases, in good quality of life
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