Abstract
Complete Response of Locally Advanced (stage III) Rectal Cancer to Metabolically Supported Chemoradiotherapy with Hyperthermia
Highlights
With nearly 1.4 million new cases diagnosed in 2012 and 607,000 deaths recorded in 2008, statistics show that worldwide colorectal cancer is the third most commonly diagnosed cancer among males and the second most commonly diagnosed cancer among females [1,2]
The patient continued receiving the same metabolically supported chemotherapy protocol followed by 60-minute local hyperthermia sessions for a 6-month-period after the second PET-CT evaluation
Advanced rectal cancer cannot be resected without a high probability of leaving microscopic or gross residual disease at the original tumor site due to tumor fixation or adherence to neighboring tissue [9]
Summary
This study, which is limited to one patient and discusses a 27-month follow-up period, demonstrates that the non-surgical treatment and achievement of complete clinical and pathological response is may be possible by means of a combination of MSCT, RT and HT
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More From: International Journal of Cancer Research and Molecular Mechanisms ( ISSN 2381-3318 )
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