Abstract
Abstract Background: The most common therapy in young multiple myeloma patients include induction, mobilization, collection and graft of peripheral blood stem cells. The present phase 2, multi-center, randomized study
Highlights
The most common therapy in young multiple myeloma patients include induction, mobilization, collection and graft of peripheral blood stem cells
Our study confirmed the existing results about grafts quality obtained with lenalidomide and the effectiveness of mobilization with cyclophosphamide and granulocyte colony stimulating factor (G-CSF), wider randomized studies should confirm the extension and implication of the observations related to response rate, overall survival and progression-free survival
The study enrolled a total of 31 patients and, 23 patients were included in the per protocol population
Summary
The main aim of the study was to compare the number of collected stem cells for transplant between both arms. The main objective of this study was to compare the total number of peripheral blood stem cell (PBSC) collected after 2 or 4 induction cycles with lenalidomide plus dexamethasone
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