Comparison of the pharmacokinetics of metronidazole in healthy female volunteers following either a single oral or intravenous dose.

Abstract

British Journal of Clinical PharmacologyVolume 8, Issue 4 p. 337-341 Free Access Comparison of the pharmacokinetics of metronidazole in healthy female volunteers following either a single oral or intravenous dose. GW Houghton, GW HoughtonSearch for more papers by this authorPS Thorne, PS ThorneSearch for more papers by this authorJ Smith, J SmithSearch for more papers by this authorR Templeton, R TempletonSearch for more papers by this authorJ Collier, J CollierSearch for more papers by this author GW Houghton, GW HoughtonSearch for more papers by this authorPS Thorne, PS ThorneSearch for more papers by this authorJ Smith, J SmithSearch for more papers by this authorR Templeton, R TempletonSearch for more papers by this authorJ Collier, J CollierSearch for more papers by this author First published: October 1979 https://doi.org/10.1111/j.1365-2125.1979.tb04715.xCitations: 48AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References FINEGOLD, S.M. & SUTTER, V.L. (1972). In Host resistance to commensal bacteria, ed. T. Mac-Phee pp 275– 297 London: Churchill Livingstone. GULAID, A., HOUGHTON, G.W., LEWELLEN, O.R.W., SMITH, J. & THORNE, P.S. (1978). Determination of metronidazole and its major metabolites in biological fluids by high pressure liquid chromatography. Br. J. clin. Pharmac., 6, 430– 432. INGHAM, H.R., RICH, G.E., SELKON, J.B., HALE, J.H., ROXBY, C.M., BETTY, M.J., JOHNSON, R.W.G. & ULDHALL, P.R. (1975). Treatment with metronidazole of three patients with serious infections due to bacteroides fragilis. J. Antimicrob. Chemother., 1, 235– 242. KHAN, A.K. & MUAZZAM, M.G. (1964). Diarrhoeal disease (Intestinal flagellates). East Pakistan med. J., 8, 18– 20. McGILL, M.I. & BLACK, M.D. (1962). Observations on the use of metronidazole in the treatment of trichomoniasis. Am. J. Obstet. Gynecol., 83, 1280– 1283. POWELL, S.J. (1969). Metronidazole in the treatment of amoebic dysentery. Med. Today, 3, 48– 53. SCHWARTZ, D.E. & JEUNET, F. (1976). Comparative pharmacokinetic studies of ornidazole and metronidazole in man. Chemotherapy, 22, 19– 29. STAMBAUGH, J.E., FEO, L.G. & MANTHEI, R.W. (1968). The isolation and identification of the urinary oxidative metabolites of metronidazole in man. J. Pharmac. exp. Ther., 161, 373– 381. TEMPLETON, R. (1977). Metabolism and pharmacokinetics of metronidazole; A review. In Metronidazole Proceedings of the International Metronidazole Conference, Montreal, Quebec, Canada, May 26–28, 1976, eds. S.M. Finegold J.A. McFadzean & F.J.C. Rowe pp. 28– 49.Princeton, New Jersey: Excerpta Medica. WELLING, P.G. & MUNRO, A.M. (1972). The pharmacoki-netics of metronidazole and tinidazole in man. Arzneimittel. Forsch., 22, 2128– 2132. Citing Literature Volume8, Issue4October 1979Pages 337-341 ReferencesRelatedInformation