Abstract
Objective: To compare the clinical efficacy and safety of ultrasound-guided microwave ablation with surgery for the treatment of primary parathyroid adenoma. Methods: The clinical data of patients with primary parathyroid adenoma admitted to the First Hospital of Yangtze University from January 2010 to May 2020 were retrospectively analyzed, and they were divided into 43 cases in the microwave ablation group (MWA) and 39 cases in the surgical procedure group (SR) according to the different treatment methods. The surgical condition, postoperative complications, and changes in serum parathyroid hormone (PTH) and serum calcium and phosphorus levels were analyzed in both groups. Results: The hospital stay and operation time of patients in the microwave ablation group were shorter than those in the surgical group, and the intraoperative bleeding was significantly less than that in the surgical group (P 0.05). There was no statistically significant difference in the incidence of postoperative complications between the two groups (P > 0.05). Conclusion: Microwave ablation can achieve the same therapeutic effect as surgery. It is a safe and feasible clinical technique worthy of clinical promotion with its short hospitalization time, less bleeding and less trauma.
Highlights
Parathyroid adenoma is one of the main causes of hyperparathyroidism, which accounts for 80% - 85% of primary hyperparathyroidism [1]
The clinical data of patients with primary parathyroid adenoma admitted to the First Hospital of Yangtze University from January 2010 to May 2020 were retrospectively analyzed, and they were divided into 43 cases in the microwave ablation group (MWA) and 39 cases in the surgical procedure group (SR) according to the different treatment methods
The surgical condition, postoperative complications, and changes in serum parathyroid hormone (PTH) and serum calcium and phosphorus levels were analyzed in both groups
Summary
Parathyroid adenoma is one of the main causes of hyperparathyroidism, which accounts for 80% - 85% of primary hyperparathyroidism [1]. Microwave ablation can inactivate adenoma activity, reduce serum parathyroid hormone and calcium levels, and alleviate adenoma-related symptoms [3]. This study will investigate the efficacy of ultrasound-guided microwave ablation treatment of parathyroid adenoma and surgical treatment, and conduct a comparative study. The efficacy of these two treatments will be studied by comparing the indexes before and after the surgery, such as preoperative and postoperative serum calcium, phosphorus and parathyroid hormone, length of hospital stay, duration of surgery, complications of laryngeal recurrent nerve injury and so on, so as to provide a better choice for the clinical treatment of parathyroid adenoma
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