Comparison of the efficacy of endoscopic retrograde pancreatic angiography and percutaneous liver puncture biliary drainage metal stent implantation in the treatment of malignant obstructive jaundice

Abstract

Objective To compare the clinical effect of ERCP and PTCD metal stent implantation in the treatment of malignant obstructive jaundice. Methods 42 patients who were treated successfully with ERCP biliary metal stent implantation in the treatment of malignant obstructive jaundice were selected as the ERCP group, 38 patients who were successfully treated with PTCD biliary metal stent implantation in the treatment of malignant obstructive jaundice, were selected as the PTCD group.The changes of alanine aminotransferase, aspartate aminotransferase, direct bilirubin, total bilirubin content and complications of patients were compared between two groups. Results On the third day of the ERCP group after operation, alanine aminotransferase, aspartate aminotransferase, direct bilirubin, total bilirubin levels were (203.94±12.53)U/L, (180.94±17.53)U/L, (185.63±17.53)μmol/L, (240.41±18.79)μmol/L respectively, those of the PTCD group were (230.63±13.95)U/L, (209.19±19.74)U/L, (192.52±16.93)μmol/L, (266.83±20.73)μmol/L respectively, which were significantly lower than before operation(all P<0.05). The incidence rate of complications of ERCP group was 4.76%, which was significantly lower than 23.68% of the PTCD group(χ2=6.02, P<0.05). Conclusion ERCP and PTCD biliary metal stent placement in the treatment of malignant obstructive jaundice can effectively relieve the obstruction.The incidence of complications of PTCD is slightly higher in both common complications. Key words: Enteroscheocele; Endoscopic retrograde pancreatic angiography; Percutaneous liver puncture biliary drainage; Metal stent implantation; Jaundice, obstructive, malignant