Comparison of real-time contrast-enhanced ultrasound and ultrasonography in the diagnosis and staging of cervical cancer

Abstract

Objective To explore the clinical value of real-time contrast-enhanced ultrasonography and ultrasonography in the diagnosis and staging of cervical cancer. Methods 80 cervical cancer patients were selected as the research subjects, they were randomly divided into two groups.40 patients in the observation group received real time contrast-enhanced ultrasound, 40 cases of the control group received conventional ultrasonography.The detection rate, diagnosis of cervical cancer, cervical cancer tissue and normal tissue parameters were compared between the two groups. Results 35 patients were detected in the observation group, the detection rate was 87.5%, 23 patients were detected in the control group, the detection rate was 57.5%, the detection rate of the observation group was significantly higher than the control group (χ2=9.028, P=0.002). In the observation group, 7 patients in stage Ⅰ(17.5%), 1 case in the control group (2.5%), there was significant difference between the two groups (χ2=5.000, P=0.025), the differences in phase Ⅱ, Ⅲ and Ⅳ were not statistically significant(P>0.05). In observation group, the peak intensity of cervical cancer was (65.43±10.55)%, and the peak time was (22.09±2.82)min, the peak intensity of normal tissue was (58.21±14.12)%, peak time was (28.27±3.01)min, the peak intensity of cervical cancer was higher than normal tissue, the peak time was shorter than normal tissues, the differences were statistically significant(t=2.590, 9.476, all P 0.05). Conclusion Compared with conventional ultrasonography, the contrast-enhanced ultrasonography can clearly show the range of tumor, quantitative analysis of time intensity curve parameters, can better reflect the characteristics of cervical cancer lesions, can improve the diagnostic rate and clear clinical stage. Key words: Ultrasonography; Uterine Cervical Neoplasms; Diagnosis