Abstract
Objective: To analyze and compare the differences of anterior segment structure parameters between pseudoexfoliation open angle glaucoma (PXOAG) and primary open angle glaucoma (POAG). Methods: This clinical case control study was conducted from December 2012 to December 2016, and the patients were selected consecutively. The PXOAG group included 54 eyes of 54 cases with an average intraocular pressure of 28.8±7.9 mmHg. The POAG group included 53 eyes of 53 cases that were matched for age, gender, and intraocular pressure, 26.3±7.4 mmHg. Anterior segment structure parameters such as corneal thickness, corneal endothelial cell density, hexagonality, anterior chamber depth, and lens thickness were measured and analyzed using independent samples t-tests. Results: For the PXOAG group, the central corneal thickness (523±41 μm), hexagonality (52%±14%), anterior chamber depth (2.79±0.60 mm), and lens thickness (4.98±0.42 mm) were not significantly different from the POAG group (t=1.57, 0.18, 1.11, 0.26, respectively, P>0.05 each). However, the corneal endothelial cell density of the PXOAG group (2 323± 451/mm2) was significantly lower than that of the POAG group (2 538±356/mm2; t=2.78, P=0.01). Conclusions: The corneal endothelial cell density of POXG patients is lower than that of POAG patients. This is a reminder to pay more attention to the protection of corneal endothelial cells during clinical treatment. Key words: pseudoexfoliation syndrome; pseudoexfoliation open-angle glaucoma; primary open-angle glaucoma; anterior segment structure parameters; corneal endothelial cell
Published Version
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