Abstract

目的 比较腹腔镜与开腹子宫肌瘤剔除术的临床效果。 方法 选择垣曲县人民医院2014年4月至2016年4月行手术治疗的子宫肌瘤(UM)患者98例,依据术式不同分为观察组(n=50)与对照组(n=48),观察组行腹腔镜子宫肌瘤剔除术,对照组行开腹子宫肌瘤剔除术治疗。比较两组术中情况、术后恢复情况、并发症发生情况及术后1年月经正常比例、子宫形态正常比例、复发情况,比较两组术前、术后1 d血清卵巢功能指标[黄体生成激素(LH)、卵泡刺激素(FSH)、雌二醇(E2)]、血清炎症及应激指标[皮质醇(Cor)、肿瘤坏死因子α(TNF-α)、白细胞介素1β(IL-1β)]水平。 结果 观察组术中出血量为(63.45±11.36)mL,少于对照组的(141.53±19.07)mL,肛门排气时间、住院时间分别为(17.07±2.68)h、(5.48±1.32)d,短于对照组的(27.66±5.42)h、(7.36±1.67)d,差异均有统计学意义(t=24.684、12.336、6.196,均P 0.05)。术后1 d观察组血清LH、FSH水平低于对照组,E2水平高于对照组,血清Cor、TNF-α、IL-1β水平低于对照组,差异均有统计学意义(t=9.836、10.041、15.150、4.318、4.840、19.414,均P<0.05)。 结论 与开腹子宫肌瘤剔除术相比,腹腔镜子宫肌瘤剔除术治疗子宫肌瘤可降低术中出血量与术后并发症发生率,加速患者术后康复,且机体炎症与应激反应轻,对卵巢功能影响小。

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