Comparison of hemodynamics in small, medium and large unruptured lateral intracranial saccular aneurysms at the internal carotid artery

Abstract

Objective To explore and compare the hemodynamic factors in small,medium and large unruptured lateral intracranial saccular aneurysms at the Internal Carotid Artery.Method 27 patient -specific unruptured lateral intracranial saccular aneurysms at the Internal Carotid Artery were divided into small,medium and large groups based on their diameters.Results models were retrospectively constructed and analyzed by computational fluid dynamic(CFD) method.Results All these three groups displayed typical lateral aneurismal flow patterns.Larger - sized group displayed more unstable flow patterns,significantly lower wall shear stress(WSS) and higher oscillatory shear index( OSI ).Conclusions These observations indicated that more unstable flow patterns,lower WSS and higher OSI in the aneurysms might be involved in increasing the risk of rupture for larger - sized unruptured lateral intracranial saccular aneurysms. Key words: Intracranial aneurysms; Lateral type; Hemodynamics; Computational fluid dynamics; Size