Abstract
Objective To study the effects between transumbilical single port laparoscopic cholecystectomy and open cholecystectomy on hepatic function and immune function in patients with gallbladder diseases.Methods 120 patients with gallbladder diseases were divided into NC group (n =58) and OC group(n =62).Then to detect the change of serum hepatic function and immune function on one day before and 3 days after the operations.Results The levels of serum hepatic function and immune function in the NC group before and after the operations were no statistical significance (t =3.94,0.13,1.34,0.76,all P ＞ 0.05),while the levels of serum hepatic function and immune function in the OC group before and after the operations have significant statistical significance (t =27.04,34.49,18.52,21.45,all P ＜ 0.05).Conclusion Transumbilical single port laparoscopic cholecystect-omy is a safe and feasible operation,which has the advantages of less effects of hepatic function and immune function to compare with open cholecystectomy. Key words: Cholecystectomy, laparoscopic ; Laparotomy; Liver function tests ; Immnity
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