Comparison of different general anesthesia method on preoperation cognitive function in elderly patients

Abstract

Objective To compare the effect of different general anesthesia method on preoperation cognitive function in elderly patients. Methods According to the digital table, 82 elderly patients (non cardiac surgical operation) were selected and divided into the two groups, each group 41 cases. The group A was given to sufentanil combined with propofol intravenous injection anesthesia, and the group B was given to sevoflurane inhalation anesthesia.The cognitive function of patients of two groups in preoperative, postoperative 3h,6h,24h were assessed by simple intelligence scale(MMSE),and the indicators of postoperative recovery were evaluated. Results The postoperative sleep time[(6.9±1.2)min],language ability recovery time[(9.8±2.2)min]in the group A were all higher than those of group B(t= 6.687,5.640,all P< 0.01). The MMSE scores in group A after 3h[(17.1±2.2) points],6h[(19.6±2.7)points],24h[(22.4±2.3)points]were lower than those of group B(t= 10.026,6.229,5.082,all P<0.01).And the PCOD rate in group A after 24h was 36.6%,which was higher than 17.1% in group B(χ2= 3.98,P< 0.05). Conclusion The inhalational anesthetic methods has more quickly postoperative recovery, lower incidence of cognitive dysfunction,better clinical effects. Key words: Anesthesia, General; Cognition Disorders