Abstract
Objective To investigate the value in MR spectrum in differential diagnosis between high grade gliomas and metastases.Methods 30 cases of patients who confirmed by histopathologic findings or clinical follow-up were collected.Using a GE Signa EXCITE HD 3.0T super conduct MR unit,all the cases of patients were performed conventional MR scan and mutlti-voxel with 2-D mutlti-voxel PRESS 144 ms.Functool software was used for post-processing of spectrum.The ratios of NAA/Cr,NAA/Cho,Cho/Cr were measured in the solid part of masses,circum of tumors and contralateral parenchyma respectively.The result was used as the statistical method by SPSS13.0 software.Results In the solid part of masses,there were significant differences between high grade gliomas and metastases in the ratios of Cho/NAA( P ＜0.05),but no differences in the ratios of Cho/Cr,NAA/Cr;In peritumoral edema,there were significant differences in the ratios of Cho/Cr,Cho/NAA ( P ＜ 0.05),but no significant differences in the ratios of NAA/Cr(P ＜ 0.05).Conclusion 1H-MRS is very important and useful in the evaluation of differential diagnosis between high grade gliomas and metastases.The inspections of the ratios of Cho/Cr,Cho/NAA of gliomas and metastases peritumoral edema are important methods,especially for solitary metastases. Key words: 1H-magnetic resonance spectroscopy; Gliomas; Multivoxel; Differential diagnosis
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