Comparative study of endoscopic ultrasonography and CT in the diagnosis of patients with pancreatic and periampullary tumors

Abstract

Objective To evaluate the clinical value of endoscopic ultrasonography and CT in the diagnosis of patients with pancreatic and periampullary tumors. Methods From February 2010 to January 2016, 89 patients with suspected pancreatic and periampullary tumors in Yinzhou Hospital Affiliated to Medical College of Ningbo University were selected in this study.Endoscopic ultrasonography and CT were performed in 89 patients.Endoscopic ultrasonography and CT examination results were compared with surgical and pathological results, and the sensitivity, specificity and accuracy of the two methods were recorded and compared. Results By pathological examination, 69 cases were diagnosed as pancreatic and periampullary tumors.The sensitivity of endoscopic ultrasonography was 95.65% (66/69), the specificity was 95.00%(19/20), and the accuracy was 95.51% (85/89). The sensitivity of CT diagnosis was 85.51% (59/69), and the specificity was 90.00%(18/20), and the accuracy was 86.52% (77/89). The sensitivity and accuracy of endoscopic ultrasonography were significantly higher than those of CT, and the differences were statistically significant (χ2=4.161, 4.395, P=0.041, 0.036). And there was no statistically significant difference in the specificity of endoscopic ultrasonography and CT (χ2=0.360, P=0.548). Conclusion Endoscopic ultrasonography and CT examination have high specificity in the diagnosis of patients with pancreatic and periampullary tumors, however, the sensitivity and accuracy of endoscopic ultrasonography are higher than CT, the clinical appropriate diagnostic methods can be chosen according to the actual condition of the patients. Key words: Pancreas; Ampulla of uater; Neoplosms; Endoscopes; Ultrasonography; Tomography, X-ray computed; Diagnosis