Abstract

Most of the epidemiological studies have shown a good relationship between blood pressure and manifestation of cardiovascular diseases (CVD). CVD has become a very common health condition that exhibits significant changes in distensibilility, compliance, and elastic modulus of the arterial vascular system. The main causes of this disease are the spreading of fats and cholesterols which initiate the damaging of endothelium, decreasing wall buffering capacity, and hardening of the arteries eventually leading to severe narrowing. We compared data from invasive and non-invasive blood pressure wave form. Using the Windkessel model, to estimate the arterial compliance as vascular index, we used data after the aortic valve closed to the end-diastolic point of blood pressure waveforms, utilized Bland-Altman difference plot, T-test, box whisker plot and scatter diagram. We analyzed physiological real data and investigated the correlation between the non-invasive and invasive blood pressure wave form. Non-invasive compressive pulse waveforms can be used to assess the total compliance of the arterial blood pressure waveforms of the invasive aorta that indicates the buffering of muscle and adipose tissue.

Highlights

  • In current times, cardiovascular diseases (CVD) have become the foremost component of mortality statistics in the world [1,2]

  • We aimed to scrutinize a method of evaluating arterial compliance using non-invasive blood pressure waveform which could be a prevailing method for medical science

  • We evaluated the time decay constant for arterial compliance of the aorta and the upper arm artery at the time end of the diastolic blood pressure using pulsator

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Summary

Introduction

Cardiovascular diseases (CVD) have become the foremost component of mortality statistics in the world [1,2]. Reports suggest that CVD will be the global health burden by 2020 [3,4] This disease follows an asymptomatic phase of development which builds up in the body silently over a period of time without any major sign on an individual’s health [5]. The rising curiosity of non-invasive arterial compliance detection led many researchers to work in the field and put forth methods to estimate the arterial compliance. The change in arterial pulse wave is a passive consequence of increase in the blood pressure. We aimed to scrutinize a method of evaluating arterial compliance using non-invasive blood pressure waveform which could be a prevailing method for medical science. This research work proved that a noninvasive method for the detection of blood pressure is significantly and more precise, compared for the invasive approach

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