Abstract
Objective The objective of this study was to evaluate the histologic grading systems for oral epithelial dysplasia (ODE). Study Design One hundred slides of ODE containing cases selected from 2 distinct oral pathology services were examined by 4 evaluators, who classified each case according to the architectural and cytologic criteria and were diagnosed according to the World Health Organization (WHO) system and binary. In addition to these 2 systems, a third form of analysis was considered, taking into account the presence or absence of ODE. Results The results were statistically analyzed in a descriptive way and by the correlation methods (Kendall tau-B and Phi test) and concordance (kappa). The WHO graduation system presented lower agreement among the evaluators; the best agreement among the evaluators occurred when considering the presence or absence of dysplasia; and in addition, it has been observed that less experienced oral pathologists tend to have more severe diagnoses than those with a longer career. Conclusions The lack of interobserver agreement was evident, highlighting the need for further studies, due to the great importance and relevance of OEDs.
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