Abstract
IntroductionTo compare and evaluate clinically and radio-graphically the bone regeneration and the amount of bone fill in intrabony component of periodontal osseous defects through the osteoconductive and osteostimulative effect of bioactive synthetic NovaBone Putty - CMF and osteoconductive effect of calcified algae-derived porous hydroxyapatite Frios® Algi-pore® bone grafts.Materials and methodsTwenty-two sites in 11 patients, within the age range of 25 to 60 years, showing intrabony defects were selected according to split mouth design and divided into group I (Frios® Algipore®) and group II (NovaBone Putty - CMF). All the selected sites were assessed with the clinical and radiographic parameters like plaque index, gingival index (full mouth and site specific), sulcus bleeding index, probing pocket depth, clinical attachment level, gingival recession, and radiographic bone fill. All the clinical and radiographic parameter values obtained at different intervals (baseline, 3, and 6 months) were subjected to statistical analysis.ResultsA statistically significant reduction in pocket depth of 2.55 ± 0.52 mm (group I), 2.64 ± 0.67 mm (group II) and gain in clinical attachment level of 7.55 ± 1.44 mm (group I), 7.55 ± 2.38 mm (group II) were recorded at the end of the study. A slight increase in gingival recession was observed. The mean percentage change in amount of radiographic bone fill of group II (71.34%) was more than group I (61.93%).ConclusionBoth NovaBone Putty - CMF and Frios® Algipore® improve healing outcomes and lead to a reduction of probing depth, a resolution of osseous defects, and a gain in clinical attachment, but radiographic observation found better results with NovaBone Putty.How to cite this articleBembi NN, Bembi S, Mago J, Baweja GK, Baweja PS. Comparative Evaluation of Bioactive Synthetic NovaBone Putty and Calcified Algae-derived Porous Hydroxyapatite Bone Grafts for the Treatment of Intrabony Defects. Int J Clin Pediatr Dent 2016;9(4):285-290.
Highlights
To compare and evaluate clinically and radiographically the bone regeneration and the amount of bone fill in intrabony component of periodontal osseous defects through the osteoconductive and osteostimulative effect of bioactive synthetic NovaBone Putty – CMF and osteoconductive effect of calcified algae-derived porous hydroxyapatite Frios® Algipore® bone grafts
Each patient selected for the study satisfied the following criteria: (i) No medical problems that would contraindicate routine periodontal surgery; (ii) patients with at least two intrabony defects, one in each quadrant or contra lateral side of the same arch with radiographic evidence of vertical/angular bone loss at affected sites; (iii) without any known allergy/hypersensitivity to any product used in the study; (iv) teeth not exhibiting grade III mobility
The results of the present study show that treatment of intrabony defects with both group I (Frios® Algipore®) and group II (NovaBone Putty – CMF) leads to significant probing dept (PD) reduction, clinical attachment loss (CAL), and clinical and radiographic bone gain compared to baseline values
Summary
To compare and evaluate clinically and radiographically the bone regeneration and the amount of bone fill in intrabony component of periodontal osseous defects through the osteoconductive and osteostimulative effect of bioactive synthetic NovaBone Putty – CMF and osteoconductive effect of calcified algae-derived porous hydroxyapatite Frios® Algipore® bone grafts. Regeneration of the periodontium must include the formation of new cementum with inserting collagen fibers on the previously periodontitis-involved root surfaces and the regrowth of the alveolar bone.[1] Conventional periodontal treatments, such as scaling and root planning are highly effective at repairing disease-related defects and halting the progression of periodontitis. They do little to promote regeneration of the lost periodontium. A myriad of choices continue to increase as new materials are developed
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