Abstract
Combined microneedling and Platelet-rich plasma in management of post-acne scars: a comparative study
Highlights
Platelet rich plasma (PRP) is an autologous solution of plasma containing [4–7] times the baseline concentration of human platelets (Leo et al, 2015).Microneedling have shown to start collagen formation and production of healing agents but without removing epidermis and without causing hyperpigmentation (Cho et al, 2008).Plasma contains autologous growth factors, which could act synergistically with growth factors induced by skin needling in order to enhance the wound-healing response. (Hom et al, 2007)
The patients were classified into 2 groups: Group A: 12 patients treated with PRP injection on the Rt side while combined microneedling with demaroller and PRP on the Lt side
Group B: 12 patients treated with PRP injection on the Rt side while combined microneedling with demapen and PRP on the Lt side
Summary
Platelet rich plasma (PRP) is an autologous solution of plasma containing [4–7] times the baseline concentration of human platelets (Leo et al, 2015).Microneedling have shown to start collagen formation and production of healing agents but without removing epidermis and without causing hyperpigmentation (Cho et al, 2008).Plasma contains autologous growth factors, which could act synergistically with growth factors induced by skin needling in order to enhance the wound-healing response. (Hom et al, 2007). Plasma contains autologous growth factors, which could act synergistically with growth factors induced by skin needling in order to enhance the wound-healing response. Platelet rich plasma (PRP) contains autologous growth factors, which could act synergistically with growth factors induced by skin needling in order to enhance the wound-healing response. Materials and methods: 24 patients with post acne scars attending outpatient clinic were offered six sessions of microneedling with PRP on one side and PRP injection on the other side of the face at an interval of 2 weeks. Conclusion: The clinical results of our study showed significant improvement using combination therapy of PRP plus dermaroller and the most significant improvement with PRP plus dermapen as compared to PRP injection.
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