The role of platelet rich plasma in management of fracture neck femur: new insights.

Abstract

The aim of this study is evaluation of the efficacy of the use of platelet rich plasma (PRP) in management of femoral neck fractures. This is a prospective study that was conducted between February 2010 and March 2013. A total of 60 patients were included in this study, categorized randomly into two groups. Group A included fracture neck femur treated by closed reduction and internal fixation with three cannulated screws and group B by addition of PRP to internal fixation. We planned to compare time of healing, need for revision and incidence of complications between the two groups. Union occurred in 53 patients (88.33%) in both groups, 25 cases (83.3%) in group A and 28 cases (93.3%) in group B, including three cases (5%) with avascular necrosis (AVN): two in group A (6.7%) and one case in group B (3.3%).Revision surgery was done for six cases (20%) in group A and for two cases (6.7%) in group B. In both groups, all united cases had good to excellent clinical outcome as regards Harris hip score (HHS) at the end of the follow up. Despite advances in surgical techniques and medical care, the risk of nonunion and avascular necrosis (AVN) after treatment of femoral neck fractures have not been changed appreciably in the last 50years. Results of this study generally showed that both the median clinical and radiographic healing time were lower in group B compared to group A.