Abstract

Purpose: To study a combined application of kinesis and laser therapy for correcting regional hemodynamic disorders in patients having dilatation cardiomyopathy (DCMP) with simultaneous supportive pharmaceutical therapy.Material and methods.100 patients with a verified diagnosis of DCMP were taken into the study. All patients had a differentiated supportive pharmtherapy. In three months after selection of the supportive differentiated drug therapy, patients were divided into two groups comparable by gender, age, disease course, severity of state and ways of medicine administration. Patients from Group 1, in addition to the supporting differentiated drug therapy, were given intravenous laser blood irradiation (ILBI) and unloading physical exercises. Patients from Group 2 continued their course of differentiated drug therapy.Research techniques included: clinical and functional observations; venous-occlusive plethysmography for assessing regional hemodynamics with a generally accepted method: measurement of blood flow (Qr) and regional vascular resistance (Rr) at rest; venous tone (Vt), reserve blood flow (QH) and regional vascular resistance (RH) under the functional loading test.Results.The data obtained during dynamic observations (in 1, 3, 6, 9 and 12 months) in Group 1 demonstrated a significant increase in volumetric blood flow velocity at rest (Qr) and reserve blood flow (QH); decrease of the regional vascular resistance at rest (Rr) and under functional loading (RH) as well as the decrease of venous tone (Vt), respectively. In Group 2 (controls), there were no significant positive dynamics; moreover, regional hemodynamics significantly worsened in 9 and 12 months.Conclusion. By the findings of venous-occlusive plethysmography, regional hemodynamics significantly improved in patients with DCMP under unloading therapeutic gymnastics in combination with ILBI and correctly selected differentiated drug therapy. The developed curative technique can be used in medical practice by GPs, therapists, cardiologists for optimizing treatment of patients with DCMP.

Highlights

  • Material and methods. 100 patients with a verified diagnosis of dilatation cardiomyopathy (DCMP) were taken into the study

  • In three months after selection of the supportive differentiated drug therapy, patients were divided into two groups comparable by gender, age, disease course, severity of state and ways of medicine administration

  • Patients from Group 2 continued their course of differentiated drug therapy.Research techniques included: clinical and functional observations; venous-occlusive plethysmography for assessing regional hemodynamics with a generally accepted method: measurement of blood flow (Qr) and regional vascular resistance (Rr) at rest; venous tone (Vt), reserve blood flow (QH) and regional vascular resistance (RH) under the functional loading test

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Summary

Оригинальные исследования Original researches

Цель исследования – изучение сочетанного применения кинезо- и лазеротерапии в целях коррекции нарушений регионарной гемодинамики у больных дилатационной кардиомиопатией (ДКМП) на фоне поддерживающей медикаментозной терапии. В 1-й группе на фоне поддерживающей дифференцированной медикаментозной терапии проводили внутривенное лазерное облучение крови (ВЛОК) и разгрузочную лечебную гимнастику; 2-я группа пациентов продолжала принимать дифференцированную медикаментозную терапию. Методы исследования включали: клинико-функциональное наблюдение; венозно-окклюзионную плетизмографию для оценки показателей регионарной гемодинамики по общепринятой методике с определением кровотока (Qr) и регионарного сосудистого сопротивления (Rr) в покое, венозного тонуса (Vt), резервного кровотока (QH) и регионарного сосудистого сопротивления (RH) на фоне функциональной нагрузочной пробы. В контрольной группе достоверной положительной динамики не было, наоборот, показатели регионарной гемодинамики через 9 и 12 месяцев наблюдения достоверно ухудшились. У больных ДКМП, по данным венозноокклюзионной плетизмографии, применение разгрузочной лечебной гимнастики в сочетании с ВЛОК на фоне рационально подобранной дифференцированной медикаментозной терапии достоверно улучшает показатели регионарной гемодинамики.

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Findings
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