Abstract
Abstract The partition chromatographic procedure which was successfully applied in last year’s collaborative study of the determination of morphine in paregoric was applied to the determination of morphine in opium. Two methods of preparation of the opium solution before partition were studied: homogenization in a high-speed blender and use of DMSO as a solvent. Reproducible results were obtained with the use of DMSO solutions. The standard deviations obtained for samples containing 7.82, 13.88, 12.45, 14.87, and 15.74% anhydrous morphine were 0.171, 0.184, 0.207, 0.220, and 0.307, respectively. From the results obtained, the method using DMSO in the preparation of the sample solution together with the partition chromatographic method is recommended for adoption as official first action.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
