Abstract
Calcium plays an important role in various stages of bone repair. Surface calcium modification is a common method to improve the biocompatibility of titanium implant. In this work, anovel facile codeposition dopamine/calcium on titanium alloy method for orthopedics applications was developed. SEM-EDS results showed calcium microspheres uniformly deposited on titanium surface with dopamine. Water contact angle showed the dopamine/calcium modification layer improved the bare titanium surface hydrophobic property. And the dopamine/calcium coating enhanced the cell proliferation by MTT test. The ALP gene expression also showed the dopamine/calcium coating may enhance the cell early differentiation. Such facile method has great potential in titanium applications.
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