Abstract

Coat color phenotypes are the result of complex interactions between hundreds of genes, only a fraction of which have been identified and characterized. Mutations that disrupt the function of the protein products of any of these genes result in the modification of phenotype and lead to the diversity of coat colors and patterns seen in animals. In an increasing number of instances, coat color phenotypes are associated with modifications in function in other organs/cell types. LYST, MC1R, TRPM1, and Agouti are a few examples of genes that influence coat color and other physiological functions.

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