Abstract
Correspondence: Jarmo Oksi Department of Infectious Diseases, Division of Medicine, Turku University Hospital; Faculty of Medicine Turku University, Turku, Finland E-mail: jarmo.oksi@utu.fi SUMMARY Clostridium difficile infection (CDI) is a major cause of hospital-acquired diarrhea and is most commonly associated with changes in normal intestinal microbiota caused by administration of antibiotics. Immunocompromized patients are on greater risk for CDI and recurrence of it. In a few years considerable amount of information has been gathered in different studies among hematologic patients with CDI. In this review the changing epidemiology and risk factors of CDI as well as its recurrence are presented. The treatment of CDI has been changed while one new compound has been approved recently and fecal microbiota transplant has been proven the most efficacious treatment for relapsing CDI. More research is needed to study the observed relationship between CDI and graft-versus-host-disease. Clostridium difficile infection: review with special interest in hematologic patients
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