Abstract
20Dec 2016 CLINICOPATHOLOGICAL SIGNIFICANCE OF CANCER STEM CELLS (CD 44 AND CD133) AND INFLAMMATORY MICROENVIRONMENT (TAMS AND MAST CELLS) IN COLORECTAL CANCER: IMMUNOHISTOCHEMICAL STUDY. Lubna O. Abdel-Salam , Hala M. El-hanbuli , Mostafa A. Abousarie and Rasha Haggag. Department of Pathology, Faculty of Medicine, Cairo University, Egypt. Department of Pathology, Faculty of Medicine, Fayoum University, Egypt. Department of Medical Oncology, Faculty of Medicine, Zagazig University, Egypt.
Highlights
Many studies have investigated the role of cancer stem cells (CSCs) and the role of the inflammatory microenvironment in Colorectal cancer (CRC) especiallyReceived: 25 October 2016 Final Accepted: 23 November 2016 Published: December 2016 their relation to prognosis
There was a statistically significant relation for CD133 expression and the (T) status of the tumor (P=0.012), while CD44 expression was significantly related to both tumor size (P=0.006) and
CD44 expression was significantly related to CD68 expression (P=0.013) but not related to the expression of CD117 (P=0.137)
Summary
CLINICOPATHOLOGICAL SIGNIFICANCE OF CANCER STEM CELLS (CD 44 AND CD133) AND INFLAMMATORY MICROENVIRONMENT (TAMS AND MAST CELLS) IN COLORECTAL CANCER: IMMUNOHISTOCHEMICAL STUDY. 1. Department of Pathology, Faculty of Medicine, Cairo University, Egypt. 2. Department of Pathology, Faculty of Medicine, Fayoum University, Egypt. 3. Department of Medical Oncology, Faculty of Medicine, Zagazig University, Egypt
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