Clinico-histopathological analysis of neoplastic and non-neoplastic lesion of ovary in Garhwal region of Uttarakhand: A 4 year study at tertiary level hospital

Abstract

Background: Aim of the study was to know various histopathological variants in ovarian lesion, its incidence with respect to age and to analyse the frequency of unilateral and bilateral lesion in Garhwal region of Uttarakhand. Material and Method: Total of 325 cases of ovarian lesions were analysed retrospectively and prospectively in a period of 4 yrs during June 2010 to June 2014 to assess the various pattern of ovarian lesion. Cases were studied in detail about complete history, clinical examination and other findings. Result: Of 325 lesions, 226 (69.54%) were non-neoplastic lesions and 99(30.46%) were neoplastic lesions. Out of the neoplastic lesions 88 were benign and 11 were malignant. The most common non-neoplastic lesion seen was follicular cysts (52.21%) followed by corpus luteal cysts (35.84%). Serous cyst adenoma was the commonest benign tumour followed by mature cystic teratoma and mucinous cyst adenoma with three cases of fibroma. Serous cystadenocarcinoma were commonest malignant tumour. Mostly cysts were bilateral. Majority of cases belonged to age group between 31 to 60 years. Conclusion: Odd geographical condition, poverty, illiteracy, lack of proper health services, lack of awareness are the main factors for late detection of ovarian lesions in this population. Clinical and histopathological examination is the main tools for early diagnosis. Newer diagnostic technique like immunohistochemistry and morphometric analysis has great prognostic significance and help to decide the line treatment. Key words: Follicular cyst, Ovarian neoplasm, Serous tumour