Clinical value of spectral CT in diagnosis of negative gallstones and common bile duct stones.

Abstract

To investigate the clinical value of spectral CT in diagnosis of negative gallstones and common bile duct stones primarily. All patients diagnosed with negative biliary stones were analyzed and examined by spectral CT scanner retrospectively. Based on acquired raw imaging data, image series were reconstructed as described below: the optimal contrast-to-noise ratio monochromatic energy images, calcium- and fat- based material decomposition images and spectral curve images. All these imaging series were analyzed quantitatively and qualitatively. The contrast between negative stones and adjacent bile was 6.87 ± 5.48 HU on hybrid energy CT images and 47.30 ± 24.05 HU on optimal monochromatic energy CT images. The mean concentration of calcium in bile and negative stones was 19.36 ± 5.12 and 3.88 ± 6.60 mg/mL, and the fat in bile and negative stones was 998.48 ± 11.79 and 1035.68 ± 15.36 mg/mL. Effective atomic number Z of negative stones (6.60 ± 0.45) was lower than that of bile (7.65 ± 0.13). The slopes of the spectral curves for negative stones were k 90-40KeV = 1.43 ± 0.63 and k 140-90KeV = 0.19 ± 0.08, and for bile, they were k 90-40KeV = -0.27 ± 0.09 and k 140-90KeV = -0.04 ± 0.01. The same stone showed different densities in different imaging groups. The positive rate of conventional CT images was lower than that of other imaging groups. Spectral CT has a high diagnostic value for negative gallstones or bile duct stones, and material decomposition CT images and spectral curves can make an accurate diagnosis.