Abstract
Objective To discuss the significance of the application of neutrophil to lymphocyte ratio (NLR) combined with prostate specific antigen (PSA) in early diagnosis of prostate carcinoma. Methods 120 cases with surgery treatment of prostate carcinoma were selected as study group, and 120 healthy people were selected as control groups.The NLR and PSA were tested to diagnose the prostate carcinoma.The critical value of NLR in diagnosing prostate carcinoma was evaluated by ROC curves, and the advantages of combination of NLR and PSA were judged. Results By using ROC curves to evaluate the NLR in diagnosis, the critical value was 2.75.The susceptibility, specificity, Youden index, correct index were 0.79, 0.85, 0.65, 0.72.The susceptibility, specificity, positive predictive value, negative predictive value, correct index of NLR combined with PSA in diagnosing the prostate carcinoma were 0.85, 0.83, 5.00, 0.18, 0.68. Conclusion The application of NLR has higher susceptibility and specificity to diagnose prostate carcinoma.NLR combined with PSA can improve the susceptibility and specificity of early diagnosis of prostate carcinoma. Key words: Prostate neoplasms; Neutrophil to lymphocyte ratio; Prostate specific antigen; Diagnosis
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