Abstract
Objective To explore the clinical value of combined detection of serum carbohydrate antigen 19-9(CA19-9) ,carcinoembryonic antigen( CEA), alpha-fetoprotein(AFP) and ferritin(Fer) in the diagnosis of digestive system neoplasm. Methods 183 cases of digestive system neoplasm and 40 patients with benign digestive diseases and 40 healthy contrll were selected. The serum tumor marker levels were detected by electrochemiluminescence assay. Results In digestive system neoplasm patients and patients with benign digestive disease, the level of the tumor markers were increased,while the detection rate of four joint detection test than a single tumor marker in digestive system neoplasm were significantly increased. Conclusion Combined detection of serum CA19-9, CEA, AFP, and Fer level, could significantly improve the sensitivity of diagnosis of digestive tract tumors. Key words: Tumor markers; Carbohydrate antigen 19-9 ; Carcinoembryonic antigen; Alpha-fetoprotein; Ferritin
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