Abstract
Objective To Observe the effects of treating primary trigeminal neuralgia with modified Shaoyao-Gancao decoction and carbamazepine. Methods 76 patients with primary trigeminal neuralgia were randomly divided into a treatment group and a control group, 38 patients in each. The treatment group was treated with modified Shaoyao-Gancao decoction and carbamazepine; and the control group was treated with carbamazepine only. Clinical curative effect, pain improvements and adverse reactions were observed after the treatment and 6 week follow-up. Results The total effective rate was 89.3%and 75.5%in the treatment group and the control group respectively, the difference was statistically significant（P=0.043）. The onset frequency, duration, degree of pain were all improved in both groups after the treatment and 6 week follow-up[treatment group after the treatment is （0.54±0.78）, （2.15±1.73）, （1.58±1.26）, 6 week follow-up is （0.24±0.63）, （1.36±1.03）,0.86±1.95）;control group after the treatment is （1.98±1.68）, （3.96±1.49）, （3.02±1.45）, 6 week follow-up is （1.06±1.78）, （1.97±1.69）, （2.13±1.54）, P〈0.05],and the treatment group was better than the control group（P=0.040 and 0.039 respectively）. Conclusion Modified Shaoyao-Gancao decoction combined carbamazepine has good clinical curative effect in treating primary trigeminal neuralgia. Key words: Shaoyao-Gancao decoction; Trigeminal neuralgia; Primary
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