Clinical study on myocardial enzymes change of patients with severe pneumonia in ICU

Abstract

Objective To observe the clinical significance of myocardial enzymes change of patients with severe pneumonia in intensive care unit (ICU). Methods 60 patients with severe pneumonia ( severe pneumonia group) and 58 patients with ordinary pneumonia( pneumonia group) were studied,and 60 healthy subjects were studied as normal control group. The CK-MB,CK,HBDH and AST levels of the research objects were analyzed by automatic chemistry analyzer. Results The enzyme indicators of severe pneumonia group were higher than the pneumonia group and normal control group, compared with the pneumonia group and normal control group, the differences were significant( all P ＜ 0. 05 ); The enzyme indicators of the pneumonia group compared with normal control group the difference was not significant(P ＞ 0. 05). The effective rate of severe pneumonia was 96.7% ,ineffective 2 cases died in the treatment. The effective rate of pneumonia group was 100.0% ,and no deaths occurred. Conclusion There was myocardial damage in patients with severe pneumonia,myocardial enzyme could be used as a valuable indicator for diagnosis, observing tendency, and predicting prognosis of patients with severe pneumonia in ICU. Key words: Intensive care unit; Severe pneumonia; Myocardial enzymes