Clinical Observation on the Application of Mifepristone and Ethacridine combined with little water-pocket induced Midtrimester Termination of Pregnancy for Women labor with Cicatricail Uterus Section

Abstract

Objective To evaluate the safety and efficacy of the mifepristone and ethacridine combined with little water-pocket induced Midtrimester Termination of prednancy for women labor with cicaricail uterus setion. Methods 160 women with as carried uterus who voluntarily under went pregnancy termination of 10-16weeks of gestation were randomly divided into 2 groups after the evaluation of the lower uterinesegmentthickness by ultrasonography. The method of the mifepristone and ethacridine combined with little water-pocket in palace cavity outside aminotic cavity on inducing labor were adopted in group A(80cases) , and mifepristone combined intra-amniotic injection of ethacridinelactate were used in group B servedascontrol. The efficacy and safety of induced labor of two groups were investigated. Results Induction-delivery inte rvaland to talstage of labour of group A were shorter than groupB ( P ＜ 0.05 ). The rate of labor within 24 hrs was higher in group A than in group B ( P ＜ 0.05 ). The volume of hemorrhage within two hours of postpartum showed nosignificant difference in two groups (P ＞ 0.05 ). No complications occur in both group. Conclusion The application of mifepristone and ethacridine combined with little water-pocket induced midtrimester termination of pregnancy for women labor with cicatricail uterus successful. Key words: Mifepristone; ethacridine; Little water-pocket; Cicatricial uterus; The intermidiate stage induces labor