Clinical observation of therapeutic endoscopic retrograde cholangiopancreatography in 1482 cases

Abstract

Objective To analyze the clinical observation and incidences of complications of therapeutic postendoscopic retrograde cholangiopancreatography(ERCP). Methods The clinical information of 1 482 cases of therapeutic ERCP was analyzed retrospectively. Results Among them,468 cases had nasal biliary drainage,532 cases had pancreatic or bile duct stent after endoscopic procedure and the other 482 case hadn't.For the drainage group,there were 396 cases of biliary stone,36 cases of simple dilatation of common bile duct,8 cases of biliary cyst,6 cases of strictured papilla,18 cases of inflammatory stricture of common bile duct,2 cases of sclerosing cholangitis and 2 cases of autoimmune pancreatitis. For the pancreatic or bile duct stent group, there were 483 cases of malignant biliary obstruction,13 cases of biliary stone,28 cases of pancreatic duct stone,3 cases of sclerosing cholangitis and 5 cases of inflammatory stricture of common bile duct.And there were 385 cases of biliary stone,36 cases of simple dilatation of common bile duct,38 cases of inflammatory stricture of common bile duct,11 cases of strictured papilla,9 cases of pancreatic duct stone and 3 cases of biliary cyst for un-drainage group.The incidences of acute pancreatitis and acute cholangitis(4.4%,2.6%)were higher in un-drainage group than the nasal biliary drainage group(1.5%,0.6%,P 0.05)and the stent group(0.4%,0.8%,P>0.05). The incidences of 4 kinds of complications were not significantly different between the nasal biliary drainage group and the stent group. Conclusion Endoscopic nasal biliary drainage or stent can prevent and treat some of therapeutic ERCP complications effectively. Key words: Endoscopic retiograde cholangiopancreatgraphy; Nasal biliary drainage; Pancreatic or bile duct stent; Complication; Prevent and treat