Abstract
Objective To evaluate the efficacy and toxicity of Gimeracil and Oteracil Porassium Capsules combined with intraperitoneal perfusion chemotherapy for the patients of stomach cancer with malignant ascites. Methods Thirty-two patients of stomach cancer with malignant ascites were received the following treatment: infusing the 0.9% NS 200 ml of DDP and recomposed human interleukin- Ⅱ , then every patient took orally Gimeracil and Oteracil Porassium Capsules 40-50 mg/d, bid from the first day to twenth-eight day. Results The total response rate was 87.5% and the clinical benefition rate was 90.6%. The main toxicity was bone marrow suppression and gastroenteric. Conclusion The Gimeracil and Oteracil Porassium Capsules combined with intraperitoneal perfusion chemotherapy is well tolerated and effective in the patients of stomach cancer with malignant ascites. Key words: Stomach cancer; Malignant ascites; Chemohyperthermia; Gimeracil and Oteracil Porassium Capsules
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