Abstract
目的 探讨临床Ⅲ期乳腺癌术前应用卡培他滨化疗的意义.方法将2000年1月2004年1月诊断的64例Ⅲ期乳腺癌随机分为两组:卡培他滨组和CAF组(环磷酰胺+阿霉素+5-氟尿嘧啶),每组各32例.分别应用卡培他滨和CAF术前化疗3个周期.结果卡培他滨组临床有效率为81.3%,CAF组临床有效率为49.3%,两组有效率比较差异有显著意义(P<0.05),且卡培他滨组临床毒副作用少.结论卡培他滨应用Ⅲ期乳腺癌术前化疗能提高临床有效率,减少毒副作用。
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