Clinical effect of Qianghuo Shengfeng decoction combined with acyclovir in the treatment of herpes simplex keratitis

Abstract

Objective To investigate the efficacy and clinical significance of Qianghuo Shengfeng decoction combined with acyclovir in the treatment of herpes simplex keratitis. Methods 98 patients with herpes simplex keratitis admitted to our hospital from July 2015 to May 2018 were divided into control group (n=49) and experimental group (n=49) according to different treatment drugs. The control group received acyclovir treatment, and the experimental group received the treatment of Qianghuo Shengfeng decoction and acyclovir. The clinical treatment effect, visual acuity and IgG and IgA content of the two groups before and after treatment were observed. Results Before treatment, there were no statistically significant differences in visual acuity, IgG and IgA content between the two groups (P>0.05); after 1 month of treatment, the visual acuity of the experimental group significantly improved, the levels of IgG and IgA significantly increased, with statistically significant differences between the two groups (P<0.05). The total effective rate of the experimental group was significantly higher than that in the control group (98.04% vs.64.71%), with statistically significant difference between the two groups (P<0.05). Conclusion The combination of Qianghuo Shengfeng decoction and acyclovir has a good clinical effect in the treatment of herpes simplex keratitis. Key words: Qianghuo Shengfeng decoction; Acyclovir; Herpes simplex keratitis