Clinical effect of Jian Shen Ping Chuan decoction combined with salbutamol sulfate aerosol in treating chronic persistent asthma

Abstract

Objective To evaluate the effect of the inhalation of healthy kidney ping chuan tang combined with salbutamol aerosol inhalation for chronic asthma. Methods A prospective randomized controlled study was conducted in 120 patients with chronic persistent asthma treated in shantou chaonan minsheng hospital from August 2016 to August 2017. There were 72 males and 48 females, aged 4 to 65 years old, with an average age of (44.58±6.89) years. This study was approved by the ethics committee of shantou chaoan minsheng hospital, and all patients and families fully informed consent and volunteered to participate in this study. An equidistant random sampling method was used to divide 120 patients into observation group and control group, with 60 cases in each group. The control group was treated by inhalation of salbutamol sulfate aerosol inhalation, and the observation group was treated with a combination of jianrenping and albuterol inhalation. Total effective rate of two groups were calculated respectively. The second forced expiratory volume (FEV1), forced vital capacity (FEV) and the maximum peak expiratory flow (PEF) before and after treatment in two groups were compared and the clinical therapeutic effect of two methods was evaluated. Results The total effective rate of treatment in the observation group was 96.67% (58/60), significantly higher than 83.33% (50/60) in the control group, and the difference was statistically significant (P 0.05), the two groups after treatment in patients with lung function index were improved to some extent, but the observation group of patients with lung function improved significantly better than that of control group (FVC: (3.43 ±3.43) L vs (2.85 ±0.59) L, FEV1: (3.01+ /-0.67) L vs (2.91+ 0.72) L, PEF: (3.51+ 3.51) L/s vs (2.56+ 0.45) L/s], the difference had statistical significance (P<0.05). Conclusion The combination of healthy kidney pingchuan tang and salbutamol aerosol can effectively relieve the clinical symptoms of patients with chronic asthma and improve lung function, and it should be widely used. Key words: Fitness Pingchuan Tang; Salbutamol sulfate aerosol; Chronic persistent asthma; Curative effect