Clinical effect of amlodipine atorvastatin calcium in the treatment of hypertensive patients with dyslipidemia

Abstract

Objective To investigate the treatment effect of amlodipine atorvastatin calcium for hypertensive patients with dyslipidemia.Methods The clinical data of 200 hypertensive patients with dyslipidemia were retrospectively studied.They were divided into the control group and the intervention group according to treatment method,100 cases in each group.The control group was given amlodipine besylate based on the conventional treatment,the intervention group was treated with amlodipine besylate and atorvastatin calcium tablets.The clinical effect was observed and compared between the two groups.Results After treatment,the systolic and diastolic blood pressure of the two groups were significantly lower than before treatment (t =4.57,5.32,4.72,4.61,all P ＜ 0.05) ; After treatment,IMT and plaque area of the two groups were obviously lower than before treatment(t =3.16,3.43,all P ＜ 0.05) ;After treatment,IMT and plaque area of the intervention group were (0.71 ± 0.29) mm and (1 t.13 ± 3.61) mm2,which were significantly lower than those of the control group [(0.82 ± 0.26) mm and (13.64 ± 2.86) mm2] (t =3.28,4.05,all P ＜ 0.05).Conclusion Amlodipine besylate and atorvastatin calcium tablets can effectively reduce hypertension,which has good synergistic effect and protective effect on blood vessels. Key words: Hypertension; Artherosclerosis ; Amlodipine and atorvastatin calcium