Abstract

Background: The incidence of twin pregnancy has been increasing worldwide and in China. This study provided a comprehensive analysis of the clinical data of twins in a Chinese tertiary hospital and summarized the clinical characteristics. Methods: A retrospective collection of data was carried out for 717 cases of twins in the Obstetrics Department of the First Affiliated Hospital of Xi’an Jiaotong University from 2011 to 2020. A comprehensive analysis of baseline information and maternal and perinatal outcomes was conducted, and the twin birth rate of the study population was also calculated. Results: The average twin delivery rate was 2.61%. A total of 206 cases were monochorionic, and 511 cases were dichorionic. Premature delivery, hypertensive disorder complicating pregnancy and premature rupture of membranes were the three most common complications. Caesarean section rates from 2011 to 2019 were maintained at 70%–80%. A total of 144 cases (20.08%) of 717 twin cases were complicated twins. Birthweight discordance ≥25% accounted for 13.53% of cases. Adverse neonatal outcomes with higher incidences were neonatal respiratory distress syndrome, small for gestational age and 1 min Apgar score ≤7. Conclusions: Twin pregnancy has different and unique clinical features. Obstetricians should pay close attention to its clinical management to obtain better perinatal outcomes.

Highlights

  • In recent years, with an increase in advanced-age pregnancies and the application of assisted reproductive technology, the incidence of twin pregnancy has been increasing worldwide and in China [1,2,3]

  • This study was designed to perform a descriptive analysis of twin pregnancies in a Chinese tertiary hospital, summarize the clinical characteristics of twin pregnancies, lay a foundation and indicate key directions for clinical diagnosis, treatment and further scientific studies

  • The twin birth rates were calculated as 2.79%, 2.59%, 2.52%, 3.12%, and 2.20%, respectively, and the average annual twin birth rate was 2.61%

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Summary

Introduction

With an increase in advanced-age pregnancies and the application of assisted reproductive technology, the incidence of twin pregnancy has been increasing worldwide and in China [1,2,3]. There are few twin studies with respect to Chinese tertiary hospitals. This study was designed to perform a descriptive analysis of twin pregnancies in a Chinese tertiary hospital, summarize the clinical characteristics of twin pregnancies, lay a foundation and indicate key directions for clinical diagnosis, treatment and further scientific studies. The incidence of twin pregnancy has been increasing worldwide and in China. This study provided a comprehensive analysis of the clinical data of twins in a Chinese tertiary hospital and summarized the clinical characteristics. A comprehensive analysis of baseline information and maternal and perinatal outcomes was conducted, and the twin birth rate of the study population was calculated. Obstetricians should pay close attention to its clinical management to obtain better perinatal outcomes

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