Clinical curative effect and safety evaluation of general surgical treatment of end-stage liver disease

Abstract

Objective To observe the clinical effectiveness and safety of general surgical treatment of end-stage liver disease. Methods One hundred and two patients with end-stage liver disease were selected, patients underwent stem cell transplantation were assigned to group A (67 cases), patients didn’t underwent stem cell transplantation were assigned to group B (35 cases). In 2, 4, 8, 12, 24 weeks after treatment, followed up and recorded changes of serum ALB, PTA, CHE, TBil and the clinical symptom scores and other indicators. The prognosis and complications were compared between the two groups, the effect and safety of the operation was evaluated. Results Followed up for 2, 4, 8, 12 and 24 weeks, the changes of serum TBil had no statistical significance (P>0.05); Followed up for 2 weeks, the changes of serum ALB, PTA, CHE between the two groups had no statistical significance (P>0.05); Followed up for 4, 8, 12 and 24 weeks, the changes of serum ALB, PTA, CHE between the two groups had statistical significance differences (P 0.05). Conclusions General surgical treatment in patients with end-stage liver disease can significantly improve the serum level of ALB, PTA, CHE, and improve the clinical symptoms of patients. Key words: End-stage liver disease; Autologous bone marrow; Stem cell transplantation; Curative effect; Safety