Abstract

目的 对脑型血吸虫病肉芽肿的临床和病理诊断进行分析.方法 将患者手术中切除的脑部病变组织,采用快速或常规石蜡包埋切片,HE染色,显微镜下观察脑血吸虫病肉芽肿的病理形态.结果 组织切片中见血吸虫病肉芽肿,急性期,中央为新鲜虫卵肉芽肿,周围大量嗜酸性粒细胞浸润,形成嗜酸性肉芽肿.慢性期为退变虫卵,其外为增生的胶质细胞,上皮样细胞和异物巨细胞,形成假结核样结节,以及纤维组织增生、胶元化.结论 血吸虫病肉芽肿是脑型血吸虫病临床表现的病理基础,以血吸虫卵为中心形成的肉芽肿病变,是脑型血吸虫病的主要病理学形态特点。

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