Abstract
This study is to examine the natural courses of Alzheimer Disease (AD), Light Cognitive Failure (LCF) and Parkinson's Dementia(PD) cases free of any therapeutic procedure and with neuropsychological test series; to determine the transformation ratio of these cases to dementia and to examine the courses of clinical factors. 120 patients consisting of 72 AD, 16 PD and 32 LCF patients and 24 healthy controls who are the spouses of the patients or healthy volunteers. Department between years 2009 - 2018, have been included in the research. In the LCF group, MMSE, forward and backward counting range, calculation, abstraction, praxis, memory of word list, understanding, construction, clock drawing scores have been higher than the other groups but lower than the control group. In the LCF group, total NPI and NPI trouble scores have been lower than the other groups. In the PD group, total NPI scores have been determined to be higher than the AD and LCF groups. Total NPI trouble score has been higher for the AD group when compared with PD and LCF groups. In the LCF group, for 11 % of the patients, diagnosis have transformed to AD in the control period. We determined that 11,1% of the patients with LCF cogenesis had transformation to AD, in this group no transformation to PD has been observed in the control time period, no transformation in the healthy control group has been observed.
Published Version
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