Abstract

Objective In order to make a clinical analysis on the leukocytes decrease caused by administration of anti-psychiatric medications of schizophrenics in hospital.Methods Taking Routine Blood Test regularly to the schizophrenics treated with anti-psychiatric medications in order to obscrve leukocytes decrease in their blood.Results While 3141 patients with Schizophrenia were treated with anti-psychiatric medications.leukocytes decrease occurred in 299 cases.with the incidence of 9.52%.Whcress 2641 schizophrenics were given only a single anti-psychiatric medication,and 239 of them had leukocytes decrease,with the incidence of 9.05%.Among 500 schizophrenics who were treated with more than one anti-psychiatric medication.leukocytes decrease occurred in 60 cases.with the incidence of 12.00%.Schizophrenics treated with novel anti-psychiatric medications had a low incidence of leukoeytes decrease;while those treated with more than one anti-psychiatric medication had a higher incidence compared with patients treated by single medicine.Conclusion Almost all anti-psychiatric medications Can cause leukocytes decrease,but this change is reversible.So it is critical to take Routine Blood Test regularly and get diagnosis and treatment early. Key words: Anti-psychiatric medication; Leukocytes decrease; Analytical investigation

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