Abstract

Objective To investigate the characteristics of clinical course in elderly patients and young-mid-dle-aged patients with upper gastrointestinal hemorrhage. Methods 417 hospitalized patients were divided into eld-edy group (≥60 yrs,198 cases) and young-middle-aged( <60 yrs,219 cases). All patients were diagnosed upper gastrointestinal hemorrhage by endoscopy. Results Endoscopy diagnosis included the first common cause to upper gastrointestinal hemorrhage was peptic ulcer, whereas more gastric ulcer were seen in elderly patients and more duo-denal ulcer were seen in young-middle-aged patients(23.7% vs 12.8%, 39.7% vs 21.7%, P <0.01). More eld-erly patients had a history of using Aspirin or NSMDs (17.1% vs 5.0%, P <0.01). The number of circulatory fail-ure and blood transfusion necessary were significantly increased, the mean duration of hospital stay was longer in eld-erly group than in young-middle-aged group(P<0.05). Conclusion The elderly patients have a more complicated clinical course than those young-mlddle-aged patients. Endoscopy is a necessary and effective method for both diagno-sis and treatment. Key words: Upper gastrointestinal hemorrhage; Aged; Young-middle-aged

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