Clinical analysis of treatment of endometriosis with modified Xiayuxue decoction

Abstract

Objective To observe the clinical effect of Xiayuxue decoction in the treatment of endometriosis. Methods 88 patients with endometriosis were selected and randomly divided into two groups by drawing lots, with 44 cases in each group.The control group received danazol treatment, the observation group was given TCM Xiayuxue decoction.Before and after treatment, the serum endocrine hormones[serum estradiol (E2), testosterone(T), progesterone(P), luteinizing hormone(LH), follicle stimulating hormone(FSH)]contents and humoral immunity(C3, C4) levels, and the clinical effect were compared between the two groups. Results After treatment, the E2, T, P, LH, FSH levels of observation group were (109.47±20.67)ng/L, (441.23±120.14)ng/L, (15.11±4.13)g/L, (9.85±2.34)IU/L, (3.05±0.90)IU/, respectively, which of the control group were (100.22±17.45)ng/L, (500.47±110.24)ng/L, (15.34±4.20)g/L, (9.01±1.04)IU/L, (3.08±0.91)IU/, respectively, there were statistically significant differences between the two groups(t=2.27, 2.41, 0.26, 2.18, 0.16, all P<0.05). The C3, C4 levels of the observation group were (1.09±0.25)g/L, (0.52±0.10)g/L, respectively, which of the control group were (1.00±0.10)g/L, (0.77±0.46)g/L, respectively, there were statistically significant differences between the two groups(t=2.23, 3.52, all P<0.05). The total effective rate of the observation group was 95.45%, which was significantly higher than 79.55% of the control group (χ2=5.09, P<0.05). Conclusion Xiayuxue decoction in the treatment of endometriosis can improve the endocrine hormone and humoral immunity of patients, and the effect is excellent. Key words: Endometriosis; Drugs, Chinese herbal; Lower blood stasis decoction