Abstract
Objective To investigate the clinical manifestation and therapy method of hyperthyroidism accompanied by liver damage. Methods To analyze the clinical data of 38 cases those with hyperthyroidism accompanied by liver damage and divide them by damage degree into two groups,one of which contains mild impairment of 26 cases and the other one contains severe impairment of 12 cases. Then make a analysis about the comparison of the two groups on the level of thyroid disorders and the correlation with liver damage. Results Of all the 38 cases 26 (68. 4％ ) cases have slight liver damage and 12(31.6％ ) cases have severe liver damage. The symptom:26 cases have abdominal distension in different degree, weakness, sickness, port colored urine, aurigo and so on. 2 cases have hepatomegaly. 10 cases have no obvious symptoms of liver damage. The FT3 and FT4 in the severely liver-impaired group is obviously higher than the slightly liver-damaged group( (t =3.16,3.27, allP ＜ 0. 05 ) ,while the TSH is obviously lower( t =3.09 ,P ＜ 0.05 ). 38 cases are all healed and the symptom of hyperthyroidism has got under control. The cases of ATD therapy or 131 I therapy are not any aggravated in liver damage. Conclusion Hyperthyroidism may lead to liver damage whose level is directly proportional to the level of thyroid dysfunction. And the result can be different, even no any symptom. Key words: Hyperthyroidism; Hepatic insufficiency
Published Version
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