Abstract
Ciprofloxacin (Chemical Abstracts Service Registry Number: 85721-33-1) is a synthetic antimicrobial agent of the fluoroquinolone class, effective in the treatment of a wide range of infections, including inhalational anthrax. Severe adverse reactions are very rare, but may be life-threatening. These include toxic epidermal necrolysis, agranulocytosis, and hypersensitivity. In addition, cross-sensitivity to other fluoroquinolones may occur. Reports of tendon rupture have been associated with ciprofloxacin use, especially with concomitant steroid therapy. Ciprofloxacin inhibits the CYP3A4 and 1A2 enzyme systems, and thus has the potential for drug interactions. Overdose of ciprofloxacin can generally be managed with supportive care, although renal failure and seizures have been reported.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call