Abstract
AbstractWe describe 20 cases of canine pyoderma responsive to immunosuppressive treatments and resembling human pyoderma gangrenosum. All dogs presented with a rapidly evolving, focal to multifocal, painful ulcerative dermatitis, non‐responsive to multiple antibiotic and anti‐inflammatory therapies. Elevations of C‐reactive protein (100%), neutrophilia (75%) and fever (25%) were also present. Histopathology showed a severe, ulcerative, superficial to deep, predominantly neutrophilic dermatitis. Bacterial infection was the most challenging differential diagnosis. Resolution of the lesions was obtained within 4–8 weeks in 83% of dogs treated with ciclosporin. Maintenance treatment was required in the majority of the dogs.
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