Abstract
In this current work, the n-hexane fraction from an ethanolic extract of pulverized peel of Ipomoea batatas Lam was subjected to chromatographic fractionation. Consequently, the fractions were investigated for their anticancer potential using the Sulforhodamine-B assay. Chromatographic fractionation led to n-hexane sub-fractions with greater anticancer potential. The study highlights the peel of Ipomoea batatas Lam as a rich dietary source of natural anticancer molecules which may be developed into nutraceuticals or serve as new leads in anticancer therapy. Keywords: Ipomoea batatas; Chromatography; Fractionation; Anticancer; Sulforhodamine-B
Highlights
Introduction starting point forHPLC isolation of novel anticancer agents.Cancer has been identified as a major cause of death in various parts of the world including the United States disease [1]
The highest anticancer inhibitory activity which was found in IB F002 c was 76.79%, 64.31%, 93.72%, 84.35% and 77.72% for colon-1, colon-2, breast, lung and head and neck cancer cell lines respectively
IB F002 a V was not tested; it was insoluble in DMSO
Summary
Introduction starting point forHPLC isolation of novel anticancer agents.Cancer has been identified as a major cause of death in various parts of the world including the United States disease [1]. Introduction starting point for HPLC isolation of novel anticancer agents. Cancer has been identified as a major cause of death in various parts of the world including the United States disease [1].
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